R2

R1

R2

R1

1a

OH

5a

OH

1b

5b

1c

5c

2a

OH

6a

OH

2b

6b

2c

6c

3a

OH

7a

OH

3b

7b

3c

7c

3d

NH2

8a

OH

4a

OH

8b

4b

8c

NH2

4c