Compound | IC50 (μMmol・L−1) | ||
| MCF-7 | NCI-H460 | SF-268 |
1 | 22.6 ± 2.4 | 18.9 ± 4.8 | 16.2 ± 2.6 |
3 | 0.02 ± 0.002 | 0.01 ± 0.002 | 0.02 ± 0.001 |
4 | 18.1 ± 0.8 | 12.3 ± 2.6 | 11.3 ± 0.8 |
5 | 0.2 ± 0.02 | 0.3 ± 0.01 | 0.2 ± 0.08 |
7 | 22.2 ± 1.4 | 16.1 ± 2.4 | 14.0 ± 1.2 |
9a | 18.6 ± 0.6 | 14.5 ± 0.8 | 22.7 ± 8.4 |
9b | 14.4 ± 8.1 | 20.2 ± 2.8 | 21.3 ± 4.2 |
9c | 0.01 ± 0.002 | 0.01 ± 0.004 | 0.01 ± 0.001 |
11 | 1.6 ± 0.4 | 2.2 ± 0. 8 | 4.0 ± 0.2 |
12 | 6.1 ± 2.4 | 8.1 ± 2.1 | 4.2 ± 1.3 |
13a | 0.6 ± 0.2 | 0.1 ± 0.02 | 0.5 ± 0.05 |
13b | 11.1 ± 2.2 | 12.2 ± 1.1 | 6.20 ± 2.4 |
13c | 0.4 ± 0.2 | 0.2 ± 0.06 | 0.5 ± 0.01 |
15 | 32.0 ± 1.6 | 40.0 ± 0.4 | 10.5 ± 1.2 |
17 | 0.01 ± 0.003 | 0.02 ± 0.001 | 0.01 ± 0.001 |
19a | 10.6 ± 4.6 | 8.5 ± 2.8 | 6.7 ± 1.4 |
19b | 0.2 ± 0.01 | 0.1 ± 0.02 | 0.2 ± 0.02 |
Doxorubicin | 0.04 ± 0.008 | 0.09 ± 0.008 | 0.09 ± 0.007 |