Compound

IC50 (μMmol・L−1)

MCF-7

NCI-H460

SF-268

1

22.6 ± 2.4

18.9 ± 4.8

16.2 ± 2.6

3

0.02 ± 0.002

0.01 ± 0.002

0.02 ± 0.001

4

18.1 ± 0.8

12.3 ± 2.6

11.3 ± 0.8

5

0.2 ± 0.02

0.3 ± 0.01

0.2 ± 0.08

7

22.2 ± 1.4

16.1 ± 2.4

14.0 ± 1.2

9a

18.6 ± 0.6

14.5 ± 0.8

22.7 ± 8.4

9b

14.4 ± 8.1

20.2 ± 2.8

21.3 ± 4.2

9c

0.01 ± 0.002

0.01 ± 0.004

0.01 ± 0.001

11

1.6 ± 0.4

2.2 ± 0. 8

4.0 ± 0.2

12

6.1 ± 2.4

8.1 ± 2.1

4.2 ± 1.3

13a

0.6 ± 0.2

0.1 ± 0.02

0.5 ± 0.05

13b

11.1 ± 2.2

12.2 ± 1.1

6.20 ± 2.4

13c

0.4 ± 0.2

0.2 ± 0.06

0.5 ± 0.01

15

32.0 ± 1.6

40.0 ± 0.4

10.5 ± 1.2

17

0.01 ± 0.003

0.02 ± 0.001

0.01 ± 0.001

19a

10.6 ± 4.6

8.5 ± 2.8

6.7 ± 1.4

19b

0.2 ± 0.01

0.1 ± 0.02

0.2 ± 0.02

Doxorubicin

0.04 ± 0.008

0.09 ± 0.008

0.09 ± 0.007