Parameters | Controls, n (%) | Cases, n (%) | p-value |
Age (years) | 57.5 ± 11.1 | 59.6 ± 12.8 | 0.054 |
Sex |
|
|
|
Male | 57 (47.5) | 82 (62.1) | 0.023 |
Female | 63 (52.5) | 50 (37.9) |
|
Anthropometry | |||
WC (cm) | 84.4 ± 8.2 | 88.8 ± 14.6 | 0.026 |
HC (cm) | 102.6 ± 10.9 | 102.0 ± 13.9 | 0.784 |
WHR | 0.8 ± 0.1 | 0.9 ± 0.1 | 0.006 |
BMI (kg/m2) | 23.4 ± 5.1 | 27.8 ± 4.7 | <0.001 |
Haemodynamic | |||
SBP (mmHg) | 123.5 ± 4.5 | 168.9 ± 20.8 | <0.001 |
DBP (mmHg) | 77.1 ± 4.3 | 99.2 ± 16.3 | <0.001 |
PP (mmHg) | 46.4 ± 5.1 | 69.7 ± 10.6 | <0.001 |
MAP (mmHg) | 92.5 ± 3.7 | 122.4 ± 17.2 | <0.001 |
Hypertension (yes) n, (%) | NA | 120 (90.9) |
|
Hypertension duration (years) | NA | 7.1 (1.4 - 16.3) |
|
Socio-demographic | |||
Past alcohol status | 73 (60.8) | 66 (50.0) | 0.234 |
Family history of HTN | 60 (50.0) | 36 (27.2) | 0.009 |
Family history of CVD | 3 (2.5) | 12 (9.1) | 0.148 |
Biochemical Assays | |||
Log renin (pg/ml) | 1.4 ± 0.1 | 1.8 ± 0.1 | <0.001 |
Log aldosterone (pg/ml) | 2.3 ± 0.2 | 2.9 ± 0.2 | <0.001 |
Log ARR | 0.9 ± 0.1 | 1.1 ± 0.2 | <0.001 |
Total cholesterol (mmol/l) | 5.2 ± 0.9 | 5.5 ± 1.4 | 0.088 |
Triglyceride (mmol/l) | 1.5 ± 0.7 | 1.2 ± 0.4 | 0.007 |
HDL-cholesterol (mmol/l) | 1.8 ± 0.3 | 1.2 ± 0.4 | <0.001 |
LDL-cholesterol (mmol/l) | 2.7 ± 0.9 | 3.9 ± 1.4 | <0.001 |
FBG (mmol/l) | 4.6 ± 0.7 | 4.9 ± 0.9 | 0.057 |