| Parameters | Number | Case (Mean ± SD) | Control (Mean ± SD) | P-value |
| Fibrinogen level mg/dL | 50 | 347.92 ± 53.78 | 228.22 ± 19.55 | 0.000 |
| CRP mg/L | 50 | 22.62 ± 14.77 | 3.36 ± 1.54 | 0.000 |
| Anti-CCP IU/mL | 50 | 14.76 ± 12.09 | 1.02 ± 0.71 | 0.000 |
| ESR mm/hour | 50 | 58.00 ± 30.96 | 7.68 ± 4.37 | 0.000 |
| R.Factor IU/mL | 50 | 35.52 ± 22.58 | 8.78 ± 4.21 | 0.000 |