Febuxostat desensitization protocol | |||||
Day | Time (minutes) | Dilution (mg/ml) | Dose (mg) | Volume (ml) | Total daily dose (mg) |
1 | 0 | 1 | 0.1 | 0.1 | 0.1 |
| 30 | 1 | 0.25 | 0.25 | 0.35 |
| 60 | 1 | 0.50 | 0.50 | 0.85 |
| 90 | 1 | 1.0 | 1 | 1.85 |
| 120 | 1 | 2.0 | 2 | 3.85 |
2 | 0 | 1 | 4 | 4 | 4 |
| 45 | 1 | 6 | 6 | 10 |
3 | 0 | 2 | 10 | 5 | 10 |
| 45 | 2 | 20 | 10 | 30 |
4 | 0 | 2 | 20 | 10 | 20 |
| 45 | 2 | 40 | 20 | 60 |
5 | 0 |
| 80 (complete tablet) |
| 80 |